Article

A higher burden of multiple sclerosis genetic risk confers an earlier onset

2020-12-21

Abstract excerpt

Multiple sclerosis is a neurodegenerative, autoimmune disease characterized by inrreversible neurological disability. The age at onset of multiple sclerosis is an objective and influential predictor of the evolution of multiple sclerosis independent of disease duration. Little is known about the mechanisms contributing to variation in onset age of multiple sclerosis, though HLA-DRB1*15:01 , the predominant risk v...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: db1aa833-3ba6-5d53-9309-1809dcd9edd6
DOI: 10.1101/2020.12.18.423477

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A higher burden of multiple sclerosis genetic risk confers an earlier onsetDOI 10.1101/2020.12.18.423477Read

A higher burden of multiple sclerosis genetic risk confers an earlier onset.Semantic proximity Read

The genetic architecture of multiple sclerosis in 2026: From susceptibility to disease progression.Semantic proximity Read

Genetic Risk in Multiple Sclerosis: Susceptibility, Modifiers and Unresolved QuestionsSemantic proximity Read

Genome‐wide association studies of multiple sclerosisSemantic proximity Read

Genetic and environmental mediators of multiple sclerosis susceptibility but not early severity run in families.Semantic proximity Read

Unlocking Multiple Sclerosis GeneticsSemantic proximity Read

The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years.Semantic proximity Read

The Multiple Sclerosis (MS) Genetic Risk Factors Indicate both Acquired and Innate Immune Cell Subsets Contribute to MS Pathogenesis and Identify Novel Therapeutic OpportunitiesSemantic proximity Read

Genetic modifiers of multiple sclerosis progression, severity and onset.Semantic proximity Read

Multiple sclerosis genetics.Semantic proximity Read

Not all roads lead to the immune system: the genetic basis of multiple sclerosis severitySemantic proximity Read

The immunogenetics of multiple sclerosis: A comprehensive review.Semantic proximity Read