Article
Microtubule-associated protein 1A is a modifier of tubby hearing (moth1).
Nature genetics - 1 Apr 2002
Ikeda Akihiro, Zheng Qing Yin, Zuberi Aamir R, Johnson Kenneth R, Naggert Jürgen K, Nishina Patsy M
Abstract excerpt
Once a mutation in the gene tub was identified as the cause of obesity, retinal degeneration and hearing loss in tubby mice, it became increasingly evident that the members of the tub gene family (tulps) influence maintenance and function of the neuronal cell lineage. Suggested molecular functions of tubby-like proteins include roles in vesicular trafficking, mediation of insulin signaling and gene transcription....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.