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Article

An allele of microtubule-associated protein 1A (Mtap1a) reduces photoreceptor degeneration in Tulp1 and Tub Mutant Mice.

Investigative ophthalmology & visual science - 1 Mar 2012

Maddox Dennis M, Ikeda Sakae, Ikeda Akihiro, Zhang Weidong, Krebs Mark P, Nishina Patsy M, Naggert Jürgen K

Abstract excerpt

PURPOSE: To identify genes that modify photoreceptor cell loss in the retinas of homozygous Tulp1(tm1Pjn) and Tub(tub) mice, which exhibit juvenile retinitis pigmentosa. METHODS: Modifier loci were identified by genetic quantitative trait locus analysis. F2 Tulp1(tm1Pjn/tm1Pjn) mutant mice from a B6-Tulp1(tm1Pjn/tm1Pjn) × AKR/J intercross were genotyped with a panel of single nucleotide polymorphism markers and...

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Share to Eye Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microtubule-Associated Proteins

Share to Photoreceptor Cells, Vertebrate

Share to Retinal Cone Photoreceptor Cells

Share to Retinal Degeneration

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Share to Retinitis Pigmentosa

Source

Open in PubMed Open full text

Identifiers

PMID: 22323461
DOI: 10.1167/iovs.11-8871
PMCID: PMC3339923

Genes

TUB
TULP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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