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Article

Genetic modification of retinal degeneration in tubby mice.

Experimental eye research - 1 Apr 2002

Ikeda Akihiro, Naggert Jürgen K, Nishina Patsy M

Abstract excerpt

Mice that carry the recessive mutation tub develop neurosensory defects including retinal and cochlear degeneration, as well as maturity-onset obesity associated with insulin resistance. The biological function of the gene and the mechanism by which it induces its phenotypes are still unclear. In order to elucidate the pathways through which tub functions, in the current study, QTL modifiers were identified in an...

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Share to Adaptor Proteins, Signal Transducing
Share to Crosses, Genetic
Share to Mice, Inbred AKR

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Photoreceptor Cells, Vertebrate

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Source

Identifiers

PMID: 12076089
DOI: 10.1006/exer.2001.1139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genetic modification of retinal degeneration in tubby mice.PMID 12076089Read ↗

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