Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The tubby-like proteins, a family with roles in neuronal development and function.

Journal of cell science - 1 Jan 2002

Ikeda Akihiro, Nishina Patsy M, Naggert Jürgen K

Abstract excerpt

The identification of a mutation at the tubby (Tub) locus, which causes obesity and neurosensory degeneration, led to the discovery of the tubby-like proteins (TULPs). Tub and the genes that encode three tubby-like proteins (TULP1- TULP3) form a novel, small gene family that plays an important role in maintenance and function of neuronal cells during development and post-differentiation. Although exploration of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Nervous System
Share to Eye Proteins
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Multigene Family

Share to Neurons

Share to Proteins

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 11801719
DOI: 10.1242/jcs.115.1.9

Genes

TUB
TULP1
TULP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The tubby-like proteins, a family with roles in neuronal development and function.PMID 11801719Read ↗

Tubby proteins: the plot thickens.Semantic proximity Read ↗

Retinal degeneration but not obesity is observed in null mutants of the tubby-like protein 1 gene.Semantic proximity Read ↗

Thyroid hormone regulates the obesity gene tub.Semantic proximity Read ↗

Prominent neuronal-specific tub gene expression in cellular targets of tubby mice mutation.Semantic proximity Read ↗

Towards understanding the function of the tubby gene family in the retina.Semantic proximity Read ↗

Efficient identification of tubby‐binding proteins by an improved system of T7 phage displaySemantic proximity Read ↗

Targeted deletion of the tub mouse obesity gene reveals that tubby is a loss-of-function mutation.Semantic proximity Read ↗

Unconventional secretion of tubby and tubby-like protein 1.Semantic proximity Read ↗

C. elegans tubby regulates life span and fat storage by two independent mechanisms.Semantic proximity Read ↗

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteinsSemantic proximity Read ↗

C-terminally mutated tubby protein accumulates in aggresomes.Semantic proximity Read ↗

Identification of rice TUBBY-like genes and their evolution.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.