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Article

Genetic modification of hearing in tubby mice: evidence for the existence of a major gene (moth1) which protects tubby mice from hearing loss.

Human molecular genetics - 1 Sept 1999

Ikeda A, Zheng Q Y, Rosenstiel P, Maddatu T, Zuberi A R, Roopenian D C, North M A, Naggert J K, Johnson K R, Nishina P M

Abstract excerpt

Quantitative trait locus (QTL) analysis of genetic crosses has proven to be a useful tool for identifying loci associated with specific phenotypes and for dissecting genetic components of complex traits. Inclusion of a mutation that interacts epistatically with QTLs in genetic crosses is a unique and potentially powerful method of revealing the function of novel genes and pathways. Although we know that a...

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Identifiers

PMID: 10441341
DOI: 10.1093/hmg/8.9.1761
PMCID: PMC3249642

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CAST
ABR

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Source receipt: pubmed, retrieved 7 Sept 2026.

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