Article
Prominent neuronal-specific tub gene expression in cellular targets of tubby mice mutation.
Human molecular genetics - 1 Sept 1998
Sahly I, Gogat K, Kobetz A, Marchant D, Menasche M, Castel M, Revah F, Dufier J, Guerre-Millo M, Abitbol M M
Abstract excerpt
The tubby strain of mice exhibits maturity-onset obesity and sensory deficits in vision and hearing. The mutated gene, tub , responsible for this phenotype was identified recently, but the function of the TUB protein has not been deduced from its amino acid sequence. This prompted us to undertake expression mapping studies with the hope that they might help to elucidate the biological role of the TUB protein. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.