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Article

Processing of pro-atrial natriuretic peptide by corin in cardiac myocytes.

The Journal of biological chemistry - 10 May 2002

Wu Faye, Yan Wei, Pan Junliang, Morser John, Wu Qingyu

Abstract excerpt

Corin is a type II transmembrane serine protease abundantly expressed in the heart. In a previous study using transfected 293 cells, we showed that corin converted pro-atrial natriuretic peptide (pro-ANP) to atrial natriuretic peptide (ANP), suggesting that corin is likely the pro-ANP convertase. Because other serine proteases such as thrombin and kallikrein had previously also been shown to cleave pro-ANP in...

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Identifiers

PMID: 11884416
DOI: 10.1074/jbc.M201503200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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