Article
A new nonparametric linkage statistic for mapping both qualitative and quantitative trait loci.
Genetic epidemiology - 1 Jan 2001
Camp N J, Gutin A, Abkevich V, Farnham J M, Cannon-Albright L, Thomas A
Abstract excerpt
We describe an alternative nonparametric linkage (NPL) statistic to that of Kruglyak et al. [Am. J. Hum. Genet. 58:1347-63, 1996] that can be used with qualitative phenotypes, and is easily extended for use with quantitative phenotypes. We analyzed the Genetic Analysis Workshop 12 simulated isolated population data, replicate 1, using two phenotypes; affected status (AFF) a dichotomous phenotype and quantitative...
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