Empirical evaluation of genome scans for linkage of a quantitative trait associated with a complex disorder.

doi:10.1002/(SICI)1098-2272(1997)14:6<927::AID-GEPI61>3.0.CO;2-N

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Article

Empirical evaluation of genome scans for linkage of a quantitative trait associated with a complex disorder.

Genetic epidemiology - 1 Jan 1997

Xu J, Panhuysen C, Taylor E, Wiesch D, Meyers D

Abstract excerpt

Nonparametric sib-pair analysis (Haseman-Elston) was used to search for evidence of linkage between a putative locus for a complex quantitative trait Q1 and genome-wide markers (367 markers from 10 chromosomes) for the first 100 replicates of nuclear family data. The characteristics of the statis...

Topics

Age Distribution
Computer Simulation
Environment
Evaluation Studies as Topic
Female
Genetic Diseases, Inborn
Genetic Linkage
Genetic Testing
Genome, Human
Humans
Male
Nuclear Family
Phenotype
Predictive Value of Tests
Quantitative Trait, Heritable
Regression Analysis
Sensitivity and Specificity
Statistics, Nonparametric

Source

Open in PubMed

Identifiers

PMID: 9433602
DOI: 10.1002/(SICI)1098-2272(1997)14:6<927::AID-GEPI61>3.0.CO;2-N

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9433602-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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