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Article

An efficient, robust and unified method for mapping complex traits (III): combined linkage/linkage-disequilibrium analysis.

American journal of medical genetics - 11 Jun 1999

Zhao L P, Quiaoit F, Aragaki C, Hsu L

Abstract excerpt

Extending the method for linkage analysis [Zhao et al., 1998a: Am. J. Med. Genet. 77:366-383; 1998b: Am. J. Med. Genet. 79:49-61], this article describes a method for the linkage-disequilibrium analysis, and for combining linkage and linkage-disequilibrium analyses. As highly dense markers are increasingly used in genome scans, one or more markers are not only linked with the disease genes if they exist, but also...

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PMID: 10360398

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