Article
Mapping genotype to phenotype for linkage analysis.
Genetic epidemiology - 1 Jan 1999
Saccone N L, Downey T J, Meyer D J, Neuman R J, Rice J P
Abstract excerpt
We model functions that use genetic information as input and trait information as output to understand genetic linkage in complex diseases. Using simulated data from GAW11, we have applied categorical classification methods and neural network analysis. We use sharing at selected markers as input, and the classification of the sib pair (for example, affected-affected or affected-unaffected) as output. In addition,...
Topics
- Chromosome Mapping
- Genetic Linkage
- Genetic Testing
- Genotype
- Humans
- Models, Genetic
- Neural Networks, Computer
- Phenotype
- Risk Factors
- Software