Segregation and linkage analysis of a quantitative versus a qualitative trait in large pedigrees.

doi:10.1002/(SICI)1098-2272(1997)14:6<999::AID-GEPI73>3.0.CO;2-F

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Article

Segregation and linkage analysis of a quantitative versus a qualitative trait in large pedigrees.

Genetic epidemiology - 1 Jan 1997

Graham J, Chapman N H, Goddard K A, Goode E L, Wijsman E M, Jarvik G P

Abstract excerpt

Goals of this analysis were to map loci contributing to variation in the quantitative trait, Q1, using the lod-score method on data set 1, and to explore the difference in power to map genes when considering the discrete vs. quantitative phenotype. Segregation analyses, after covariate adjustment...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 8
Genetic Linkage
Humans
Lod Score
Meiosis
Pedigree
Phenotype
Quantitative Trait, Heritable

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