Article
Roles for zebrafish focal adhesion kinase in notochord and somite morphogenesis.
Developmental biology - 15 Dec 2001
Henry C A, Crawford B D, Yan Y L, Postlethwait J, Cooper M S, Hille M B
Abstract excerpt
We have cloned zebrafish focal adhesion kinase (Fak) and analyzed its subcellular localization. Fak protein is localized at the cortex of notochord cells and at the notochord-somite boundary. During somitogenesis, Fak protein becomes concentrated at the basal region of epithelial cells at intersomitic boundaries. Phosphorylated Fak protein is seen at both the notochord-somite boundary and intersomitic boundaries,...
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