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Article

Snail1 controls epithelial-mesenchymal lineage commitment in focal adhesion kinase-null embryonic cells.

The Journal of cell biology - 28 Nov 2011

Li Xiao-Yan, Zhou Xiaoming, Rowe R Grant, Hu Yuexian, Schlaepfer David D, Ilić Dusko, Dressler Gregory, Park Ann, Guan Jun-Lin, Weiss Stephen J

Abstract excerpt

Mouse embryonic cells isolated from focal adhesion kinase (FAK)-null animals at embryonic day 7.5 display multiple defects in focal adhesion remodeling, microtubule dynamics, mechanotransduction, proliferation, directional motility, and invasion. To date, the ability of FAK to modulate cell function has been ascribed largely to its control of posttranscriptional signaling cascades in this embryonic cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22105351
DOI: 10.1083/jcb.201105103
PMCID: PMC3257570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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