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Article

Control of motile and invasive cell phenotypes by focal adhesion kinase.

Biochimica et biophysica acta - 5 Jul 2004

Schlaepfer David D, Mitra Satyajit K, Ilic Dusko

Abstract excerpt

Cell motility is stimulated by extracellular stimuli and initiated by intracellular signaling proteins that localize to sites of cell contact with the extracellular matrix termed focal contacts. Focal adhesion kinase (FAK) is an intracellular protein-tyrosine kinase (PTK) that acts to regulate the cycle of focal contact formation and disassembly required for efficient cell movement. FAK is activated by a variety...

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Source

Identifiers

PMID: 15246681
DOI: 10.1016/j.bbamcr.2004.04.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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