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Article

Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development.

The Journal of clinical investigation - 1 Aug 2009

Vallejo-Illarramendi Ainara, Zang Keling, Reichardt Louis F

Abstract excerpt

Neural crest cells (NCCs) participate in the remodeling of the cardiac outflow tract and pharyngeal arch arteries during cardiovascular development. Focal adhesion kinase (FAK) mediates signal transduction by integrin and growth factor receptors, each of which is important for normal cardiovascul...

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Share to Craniofacial Abnormalities
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19587446
DOI: 10.1172/JCI38194
PMCID: PMC2719938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19587446-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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