Article
Vessel patterning in the embryo of the zebrafish: guidance by notochord.
Developmental biology - 1 Mar 1997
Fouquet B, Weinstein B M, Serluca F C, Fishman M C
Abstract excerpt
We have cloned the zebrafish homolog of the receptor tyrosine kinase flk-1 to provide us with a tool to study normal vascular pattern formation in the developing zebrafish embryo and to compare it to mutants in which vascular pattern is perturbed. We find that during normal development the first angioblasts arise laterally in the mesoderm and then migrate medially to form the primordia of the large axial vessels,...
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