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Article

Integrin α5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish.

Molecular biology of the cell - 1 Dec 2012

Hayes Julie M, Hartsock Andrea, Clark Brian S, Napier Hugh R L, Link Brian A, Gross Jeffrey M

Abstract excerpt

Lens fiber formation and morphogenesis requires a precise orchestration of cell- extracellular matrix (ECM) and cell-cell adhesive changes in order for a lens epithelial cell to adopt a lens fiber fate, morphology, and migratory ability. The cell-ECM interactions that mediate these processes are largely unknown, and here we demonstrate that fibronectin1 (Fn1), an ECM component, and integrin α5, its cellular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23097490
DOI: 10.1091/mbc.E12-09-0672
PMCID: PMC3521681

Genes

ILK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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