Article
[Clearing up the p16INK4a-p14/p19ARF imbroglio?].
Bulletin du cancer - 1 Nov 2001
Larsen C J
Abstract excerpt
Since its discovery, the CDKN2/MTS1 locus has been considered as an important site for the understanding of cell cycle deregulations that are involved in cancer cell generation. A comprehensive approach of the respective roles played by the two p16INK4a and p14/p19ARF (ARF) proteins encoded by this locus was not yet achieved because of the structural intrication of their genes. Inactivation of the only p16INK4a...
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