[Clearing up the p16INK4a-p14/p19ARF imbroglio?].

Article

[Clearing up the p16INK4a-p14/p19ARF imbroglio?].

Bulletin du cancer - 1 Nov 2001

Larsen C J

Abstract excerpt

Since its discovery, the CDKN2/MTS1 locus has been considered as an important site for the understanding of cell cycle deregulations that are involved in cancer cell generation. A comprehensive approach of the respective roles played by the two p16INK4a and p14/p19ARF (ARF) proteins encoded by th...

Topics

Animals
Carcinogens
Cell Division
Cell Transformation, Neoplastic
Cellular Senescence
Cyclin-Dependent Kinase Inhibitor p16
Fibroblasts
Gene Silencing
Genes, Tumor Suppressor
Genetic Predisposition to Disease
Humans
Mice
Neoplasms
Tumor Suppressor Protein p14ARF

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