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Article

The tumor suppressor protein p16INK4a.

Experimental cell research - 25 Nov 1997

Serrano M

Abstract excerpt

The tumor suppressor protein p16INK4a (inhibitor of CDK4) is one of the most direct links between cell-cycle control and cancer. The p16INK4a gene is frequently inactivated in human tumors, and inheritance of mutant alleles results in susceptibility to several types of cancer. p16INK4a is part of...

Topics

Alleles
Animals
Cell Cycle
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinases
Genes, p16
Humans
Mammals
Models, Biological
Neoplasms
Proteins
Retinoblastoma Protein
Tumor Suppressor Protein p14ARF

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9417860
DOI: 10.1006/excr.1997.3824

Genes

CDK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9417860-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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