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Article

Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Dec 2001

Walters C L, Blendy J A

Abstract excerpt

Addiction is a complex process that relies on the ability of an organism to integrate positive and negative properties of drugs of abuse. Therefore, studying the reinforcing as well as aversive components of drugs of abuse in a single model system will enable us to understand the role of final common mediators, such as cAMP response element-binding protein (CREB), in the addiction process. To this end, we...

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Identifiers

PMID: 11717377
PMCID: PMC6763933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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