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Article

A polymorphism of the CREB binding protein (CREBBP) gene is a risk factor for addiction.

Brain research - 11 Aug 2011

Kumar Deepak, Deb Ishani, Chakraborty Japashish, Mukhopadhyay Sikha, Das Sumantra

Abstract excerpt

Unequivocal evidences have implicated c-AMP response element binding protein (CREB) in drug addiction. Recent reports indicate that the CREB binding protein (CREBBP), a transcription co-activator, may also be involved in the sensitivity to drugs of abuse. We undertook studies on the single nucleotide polymorphisms (SNP) at selective areas of CREBBP gene in heroin as well as in alcohol addicts and compared them...

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Source

Identifiers

PMID: 21752352
DOI: 10.1016/j.brainres.2011.05.048

Genes

CREBBP

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