Article
Sensitivity to cocaine in adult mice is due to interplay between genetic makeup, early environment and later experience.
Neuropharmacology - 1 Oct 2017
Di Segni Matteo, Andolina Diego, Coassin Alessandra, Accoto Alessandra, Luchetti Alessandra, Pascucci Tiziana, Luzi Carla, Lizzi Anna Rita, D'Amato Francesca R, Ventura Rossella
Abstract excerpt
Although early aversive postnatal events are known to increase the risk to develop psychiatric disorders later in life, rarely they determine alone the nature and outcome of the psychopathology, indicating that interaction with genetic factors is crucial for expression of psychopathologies in adulthood. Moreover, it has been suggested that early life experiences could have negative consequences or confer adaptive...
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