Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The RepA protein of plasmid pSC101 controls Escherichia coli cell division through the SOS response.

Molecular microbiology - 1 Oct 2001

Ingmer H, Miller C, Cohen S N

Abstract excerpt

Although plasmid copy number varies widely among different plasmid species, normally copy number is maintained within a narrow range for any given plasmid. Such copy number control has been shown to occur by regulation of the rate of plasmid DNA replication. Here we report a novel mechanism by which the pSC101 plasmid also can detect an imbalance between the cellular level of its replication protein, RepA, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Bacterial
Share to DNA Helicases
Share to DNA Primase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to Gene Dosage

Share to Gene Expression Regulation, Bacterial

Share to SOS Response, Genetics

Share to Trans-Activators

Source

Identifiers

PMID: 11703672
DOI: 10.1046/j.1365-2958.2001.02661.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The RepA protein of plasmid pSC101 controls Escherichia coli cell division through the SOS response.PMID 11703672Read ↗

Excess intracellular concentration of the pSC101 RepA protein interferes with both plasmid DNA replication and partitioning.Semantic proximity Read ↗

Isolation and characterization of plasmid mutations that enable partitioning of pSC101 replicons lacking the partition (par) locus.Semantic proximity Read ↗

Isolation and characterization of novel mutations in the pSC101 origin that increase copy number.Semantic proximity Read ↗

Novel alleles of the Escherichia coli dnaA gene are defective in replication of pSC101 but not of oriC.Semantic proximity Read ↗

Replication origin mutations affecting binding of pSC101 plasmid-encoded Rep initiator protein.Semantic proximity Read ↗

Analysis of a copy number mutant of plasmid pSC101: co-maintenance of wild type and mutant plasmids.Semantic proximity Read ↗

In vivo and in vitro studies of a copy number mutation of the RepA replication protein of plasmid pSC101.Semantic proximity Read ↗

Modulation of pPS10 host range by plasmid-encoded RepA initiator protein.Semantic proximity Read ↗

A dnaC mutation in Escherichia coli that affects copy number of ColE1-like plasmids and the PriA-PriB (but not Rep-PriC) pathway of chromosomal replication restart.Semantic proximity Read ↗

Boundaries of the pSC101 minimal replicon are conditional.Semantic proximity Read ↗

A copy-number mutant of plasmid pSC101.Semantic proximity Read ↗

Positive and negative regulations of plasmid CoLIb-P9 repZ gene expression at the translational level.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.