Novel alleles of the Escherichia coli dnaA gene are defective in replication of pSC101 but not of oriC.

doi:10.1128/jb.177.22.6657-6665.1995

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Article

Novel alleles of the Escherichia coli dnaA gene are defective in replication of pSC101 but not of oriC.

Journal of bacteriology - 1 Nov 1995

Sutton M D, Kaguni J M

Abstract excerpt

Five novel alleles of the Escherichia coli dnaA gene that were temperature sensitive in maintenance of pSC101, a plasmid that is dependent on this gene for replication, were isolated. Nucleotide sequence analysis revealed that four of the five alleles arose from single base substitutions, whereas...

Topics

Alleles
Bacterial Proteins
Base Sequence
DNA Helicases
DNA Replication
DNA-Binding Proteins
Escherichia coli
Molecular Sequence Data
Plasmids
Point Mutation
Proteins
Replication Origin
Sequence Analysis, DNA
Temperature
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