Isolation and characterization of plasmid mutations that enable partitioning of pSC101 replicons lacking the partition (par) locus.

doi:10.1128/jb.177.4.1086-1089.1995

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Article

Isolation and characterization of plasmid mutations that enable partitioning of pSC101 replicons lacking the partition (par) locus.

Journal of bacteriology - 1 Feb 1995

Conley D L, Cohen S N

Abstract excerpt

Second-site mutations that allow stable inheritance of partition-defective pSC101 plasmids mapped to seven distinct sites in the 5' half of the plasmid repA gene. While the mutations also elevated pSC101 copy number, there was no correlation between copy number increase and plasmid stability. Com...

Topics

Bacterial Proteins
Cell Division
DNA Helicases
DNA Replication
DNA-Binding Proteins
Escherichia coli
Integration Host Factors
Mutation
Plasmids
Proteins
Replicon
Sequence Deletion
Suppression, Genetic
Trans-Activators

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