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Article

Isolation and characterization of plasmid mutations that enable partitioning of pSC101 replicons lacking the partition (par) locus.

Journal of bacteriology - 1 Feb 1995

Conley D L, Cohen S N

Abstract excerpt

Second-site mutations that allow stable inheritance of partition-defective pSC101 plasmids mapped to seven distinct sites in the 5' half of the plasmid repA gene. While the mutations also elevated pSC101 copy number, there was no correlation between copy number increase and plasmid stability. Combinations of mutations enabled pSC101 DNA replication in the absence of integration host factor and also stabilized...

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Identifiers

PMID: 7860588
DOI: 10.1128/jb.177.4.1086-1089.1995
PMCID: PMC176706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Isolation and characterization of plasmid mutations that enable partitioning of pSC101 replicons lacking the partition (par) locus.PMID 7860588Read ↗

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