Article
Base mutation analysis by a ferrocenyl naphthalene diimide derivative.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2000
Takenaka S, Miyahara H, Yamashita K, Takagi M, Kondo H
Abstract excerpt
An electrochemical DNA sensing technique was developed by using ferrocenyl naphthalene diimide coupled with a probe DNA-immobilized electrode. This technique enabled detection of target DNA quickly and with high sensitivity. Applicability of this technique for single nucleotide polymorphisms (SNPs) analysis was demonstrated by successful analysis of a DNA mismatch on the cancer repression gene p53 with high...
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