Article
Reactivity of ferrocenylcarbodiimide with DNA duplex containing single-mismatched base pairs.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry - 1 Jun 2007
Mukumoto Kosuke, Watanabe Sadayoshi, Nojima Takahiko, Waki Michinori, Takenaka Shigeori
Abstract excerpt
Ferrocenylcarbodiimide (1), which is known to react with a guanine (G) or thymine (T) base of single stranded DNA, was allowed to react with DNA duplex having a single mismatched base pair of G-T, T-T, or T-cytosine (C). Electrophoreograms of the reaction mixture showed that 1 could react with G or T base of the mismatched sites on the DNA duplex. However, 1 also reacted with the G base of the terminal site on...
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