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Article

DNA single-base mismatch study with an electrochemical enzymatic genosensor.

Biosensors & bioelectronics - 15 Mar 2007

Abad-Valle Patricia, Fernández-Abedul M Teresa, Costa-García Agustín

Abstract excerpt

A thorough selectivity study of DNA hybridization employing an electrochemical enzymatic genosensor is discussed here. After immobilizing on a gold film a 30-mer 3'-thiolated DNA strand, hybridization with a biotinylated complementary one takes place. Then, alkaline phosphatase is incorporated to the duplex through the interaction streptavidin-biotin. Enzymatic generation of indigo blue from 3-indoxyl phosphate...

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Identifiers

PMID: 16950611
DOI: 10.1016/j.bios.2006.07.015
PMCID: PMC7127251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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