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SNP analysis by using ferrocenyl naphthalene diimide (FND)-based electrochemical hybridization assay (EHA).

Nucleic acids research. Supplement (2001) - 1 Jan 2003

Sato Shinobu, Maeda Yuki, Nojima Takahiko, Kondo Hiroki, Takenaka Shigeori

Abstract excerpt

Ferrocenylnaphthalene diimide (FND) having double-stranded DNA preference was used as an electrochemical hybridization indicator and applied to the electrochemical hybridization assay (EHA) coupled with a DNA probe-immobilized gold electrode. The effect of DNA probe length and the position of SNP (single nucleotide polymorphism) site on the DNA probe were studied in the SNP analysis concerned with the side effect...

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PMID: 14510434
DOI: 10.1093/nass/3.1.169

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