Article
Electrochemical and fluorescence detection of cytosine-related SNPs using a ferrocenyl naphthyridine derivative.
Nucleic acids symposium series (2004) - 1 Jan 2007
Morita Kotaro, Sato Yusuke, Seino Takehiro, Nishizawa Seiichi, Teramae Norio
Abstract excerpt
A novel hydrogen bond-forming ligand for cytosine-related single nucleotide polymorphism, which contains both a fluorescent naphthyridine moiety and a ferrocene group as an electrochemical indicator, is described. Hydrogen bond-mediated recognition for a target nucleobase within an abasic site-containing DNA duplex was confirmed by both fluorescence and electrochemical measurements. The analysis by fluorescence...
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