Article
A smart DNA-gold nanoparticle probe for detecting single-base changes on the platform of a quartz crystal microbalance.
Chemical communications (Cambridge, England) - 18 Mar 2015
Li Hui, Xiao Shiyan, Yao Dongbao, Lam Michael Hon-Wah, Liang Haojun
Abstract excerpt
A design of DNA-gold nanoparticle probe-fueled DNA strand displacements for detecting single-base changes on the platform of a quartz crystal microbalance with random sequences was developed. After optimizing and testing the detection system, it has been successfully applied to detect mutation of a realistic sequence associated with human cancer, thereby indicating that this method has potential applicability in...
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