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Article

Quartz crystal microbalance detection of DNA single-base mutation based on monobase-coded cadmium tellurium nanoprobe.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry - 1 Jan 2011

Zhang Yuqin, Lin Fanbo, Zhang Youyu, Li Haitao, Zeng Yue, Tang Hao, Yao Shouzhuo

Abstract excerpt

A new method for the detection of point mutation in DNA based on the monobase-coded cadmium tellurium nanoprobes and the quartz crystal microbalance (QCM) technique was reported. A point mutation (single-base, adenine, thymine, cytosine, and guanine, namely, A, T, C and G, mutation in DNA strand, respectively) DNA QCM sensor was fabricated by immobilizing single-base mutation DNA modified magnetic beads onto the...

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PMID: 22156252
DOI: 10.2116/analsci.27.1229

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