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DNA abasic site-directed formation of fluorescent silver nanoclusters for selective nucleobase recognition.

Nanotechnology - 29 Jul 2011

Ma Kun, Cui Qinghua, Liu Guiying, Wu Fei, Xu Shujuan, Shao Yong

Abstract excerpt

DNA single-nucleotide polymorphism (SNP) detection has attracted much attention due to mutation related diseases. Various methods for SNP detection have been proposed and many are already in use. Here, we find that the abasic site (AP site) in the DNA duplex can be developed as a capping scaffold for the generation of fluorescent silver nanoclusters (Ag NCs). As a proof of concept, the DNA sequences from...

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PMID: 21719966
DOI: 10.1088/0957-4484/22/30/305502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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