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Article

alpha-Synuclein gene haplotypes are associated with Parkinson's disease.

Human molecular genetics - 15 Aug 2001

Farrer M, Maraganore D M, Lockhart P, Singleton A, Lesnick T G, de Andrade M, West A, de Silva R, Hardy J, Hernandez D

Abstract excerpt

We report haplotype analysis of the alpha-synuclein gene in Parkinson's disease (PD), extending earlier reports of an association with a polymorphism within the gene promoter. This analysis showed significant differences in haplotypes between PD cases and controls. Our analyses demonstrate that genetic variability in the alpha-synuclein gene is a risk factor for the development of PD. These genetic findings are...

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Identifiers

PMID: 11532993
DOI: 10.1093/hmg/10.17.1847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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