Article
Association of alpha-synuclein gene haplotypes with Parkinson's disease.
Parkinsonism & related disorders - 1 Aug 2007
Parsian A J, Racette B A, Zhao J H, Sinha R, Patra B, Perlmutter J S, Parsian A
Abstract excerpt
In a previous study, we detected an association between a dinucleotide repeat (Rep1) in the alpha-Synuclein (SNCA) gene and sporadic Parkinson's disease (PD). To extend our previous finding in a larger sample and further determine the role of SNCA in the development of PD, we screened a sample of 194 familial PD (FPD), 327 sporadic PD (SPD), and 215 controls with the Rep1 marker and 2 single nucleotide...
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