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Article

α‐Synuclein promoter confers susceptibility to Parkinson's disease

28 Sept 2004

Abstract excerpt

Familial Parkinson's disease (PD) has been linked to missense and genomic multiplication mutations of the alpha-synuclein gene (SNCA). Genetic variability within SNCA has been implicated in idiopathic PD in many populations. We now confirm and extend these findings, within a Belgian sample, using a high-resolution map of genetic markers across the SNCA locus. Our study implicates the SNCA promoter in...

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PMID: 15455394
DOI: 10.1002/ana.20268

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