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Article

Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo

31 Jul 2001

Abstract excerpt

A noninvasive method for molecular imaging of the activity of different signal transduction pathways and the expression of different genes in vivo would be of considerable value. It would aid in understanding the role specific genes and signal transduction pathways have in various diseases, and could elucidate temporal dynamics and regulation at different stages of disease and during various therapeutic...

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PMID: 11481488
DOI: 10.1073/pnas.161091198

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