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Article

Ionizing radiation-induced gene expression changes in TP53 proficient and deficient glioblastoma cell lines.

Mutation research - 30 Aug 2013

Godoy P R D V, Mello S S, Magalhães D A R, Donaires F S, Nicolucci P, Donadi E A, Passos G A, Sakamoto-Hojo E T

Abstract excerpt

The genetic heterogeneity presented by different cell lines derived from glioblastoma (GBM) seems to influence their responses to antitumoral agents. Although GBM tumors present several genomic alterations, it has been assumed that TP53, frequently mutated in GBM, may to some extent be responsible for differences in cellular responses to antitumor agents, but this is not clear yet. To directly determine the...

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Source

Identifiers

PMID: 23817105
DOI: 10.1016/j.mrgentox.2013.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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