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Positron Emission Tomography Reporter Genes and Reporter Probes: Gene and Cell Therapy Applications

1 Jan 2012

Abstract excerpt

Positron emission tomography (PET) imaging reporter genes (IRGs) and PET reporter probes (PRPs) are amongst the most valuable tools for gene and cell therapy. PET IRGs/PRPs can be used to non-invasively monitor all aspects of the kinetics of therapeutic transgenes and cells in all types of living mammals. This technology is generalizable and can allow long-term kinetics monitoring. In gene therapy, PET IRGs/PRPs...

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PMID: 22509201
DOI: 10.7150/thno.3677

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