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Article

Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53.

Proceedings of the National Academy of Sciences of the United States of America - 23 Jan 1996

Morris G F, Bischoff J R, Mathews M B

Abstract excerpt

Proliferating-cell nuclear antigen (PCNA) is a DNA damage-inducible protein that performs an essential function in DNA replication and repair as an auxiliary factor for DNA polymerases delta and epsilon. Examination of the human PCNA promoter DNA sequence revealed a site with homology to the consensus DNA sequence bound by p53. PCNA promoter fragments with this site intact bound p53 in vitro and were...

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Source

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Identifiers

PMID: 8570655
DOI: 10.1073/pnas.93.2.895
PMCID: PMC40154

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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