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Article

Site-directed spin-labeling analysis of reconstituted Mscl in the closed state.

The Journal of general physiology - 1 Aug 2001

Perozo E, Kloda A, Cortes D M, Martinac B

Abstract excerpt

The mechanosensitive channel from Escherichia coli (Eco-MscL) responds to membrane lateral tension by opening a large, water-filled pore that serves as an osmotic safety valve. In an attempt to understand the structural dynamics of MscL in the closed state and under physiological conditions, we have performed a systematic site-directed spin labeling study of this channel reconstituted in a membrane bilayer....

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Share to Crystallography
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11479346
DOI: 10.1085/jgp.118.2.193
PMCID: PMC2233830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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