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Article

State-stabilizing Interactions in Bacterial Mechanosensitive Channel Gating and Adaptation.

The Journal of biological chemistry - 17 Jul 2009

Anishkin Andriy, Sukharev Sergei

Abstract excerpt

We outline several principles that we believe define the gating of two bacterial mechanosensitive channels, MscL and MscS. Serving as turgor regulators in bacteria and other walled cells, these molecules are tangible models for studying conformational transitions in membrane proteins driven directly by membrane tension. MscL, a compact pentamer, reversibly opens a gigantic 30-A pore at near-lytic tensions. MscS,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mechanotransduction, Cellular

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Source

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Identifiers

PMID: 19383606
DOI: 10.1074/jbc.R109.009357
PMCID: PMC2740535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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State-stabilizing Interactions in Bacterial Mechanosensitive Channel Gating and Adaptation.PMID 19383606Read ↗

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