Use of transgenics, null mutants, and antisense approaches to study ethanol's actions.

doi:10.1111/j.1530-0277.1995.tb00951.x

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Article

Use of transgenics, null mutants, and antisense approaches to study ethanol's actions.

Alcoholism, clinical and experimental research - 1 Aug 1995

Wehner J M, Bowers B J

Abstract excerpt

Behavioral and biochemical responses mediating ethanol's actions have been difficult to study in humans and animals because of their complex polygenic nature. Recent progress in the creation of new animal models using recombinant DNA technology has provided a set of genetic tools by which the rol...

Topics

Alcohol Withdrawal Delirium
Alcoholism
Animals
DNA, Antisense
DNA, Recombinant
Drug Tolerance
Female
Male
Mice
Mice, Knockout
Mice, Transgenic
Models, Genetic
Nerve Tissue Proteins
Phenotype

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