Article
Characterization of the mouse adenylyl cyclase type VIII gene promoter: regulation by cAMP and CREB.
The European journal of neuroscience - 1 Oct 2002
Chao Jennifer R, Ni Yan G, Bolaños Carlos A, Rahman Zia, DiLeone Ralph J, Nestler Eric J
Abstract excerpt
Adenylyl cyclase (AC) type VIII has been implicated in several forms of neural plasticity, including drug addiction and learning and memory. In the present study, we directly examined the role for the transcription factor CREB (cAMP response element binding protein) in regulating ACVIII expression by cloning a 5.2 kilobase region upstream of the translation start site of the mouse ACVIII gene. Analysis of this...
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