Article
Sample size calculations for classical association and TDT-type methods using family data.
Annals of human genetics - 1 May 2001
Tregouet D A, Pallaud C, Sass C, Visvikis S, Tiret L
Abstract excerpt
Transmission Disequilibrium Test (TDT)-based methods have been advocated by several authors for testing that a marker-phenotype association is actually due to linkage and not to uncontrolled stratification. As a pre-requisite of TDT-type methods is the presence of an association between marker and phenotype, one may wish to first investigate the association using a classical association study, and then to check...
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