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Article

Analytic power and sample size calculation for the genotypic transmission/disequilibrium test in case-parent trio studies.

Biometrical journal. Biometrische Zeitschrift - 1 Nov 2014

Neumann Christoph, Taub Margaret A, Younkin Samuel G, Beaty Terri H, Ruczinski Ingo, Schwender Holger

Abstract excerpt

Case-parent trio studies considering genotype data from children affected by a disease and their parents are frequently used to detect single nucleotide polymorphisms (SNPs) associated with disease. The most popular statistical tests for this study design are transmission/disequilibrium tests (TDTs). Several types of these tests have been developed, for example, procedures based on alleles or genotypes....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25123830
DOI: 10.1002/bimj.201300148
PMCID: PMC4206700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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