Article
Power comparison of regression methods to test quantitative traits for association and linkage.
Genetic epidemiology - 1 Apr 2000
Zhu X, Elston R C
Abstract excerpt
George et al. [1999 Am J Hum Genet 65:236-245] proposed a regression-based TDT method for quantitative traits consisting of regressing the trait on the parental transmission of a marker allele. Zhu and Elston [2000] also developed a TDT method for quantitative traits by defining a linear transformation to condition out founder information. Both methods test the null hypothesis of no linkage or association and can...
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