Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The haplotype-relative-risk (HRR) method for analysis of association in nuclear families.

American journal of human genetics - 1 Jun 1993

Knapp M, Seuchter S A, Baur M P

Abstract excerpt

One major problem in studying an association between a marker locus and a disease is the selection of an appropriate group of controls. However, this problem of population stratification can be circumvented in a quite elegant manner by family-based methods. The haplotype-relative-risk (HRR) method, which samples nuclear families with a single affected child and uses the parental haplotypes not transmitted to that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genetic Markers
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Models, Genetic

Share to Phenotype

Share to Recombination, Genetic

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 8503442
PMCID: PMC1682286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The haplotype-relative-risk (HRR) method for analysis of association in nuclear families.PMID 8503442Read ↗

Analysis of case-parental control studies: method for the study of associations between disease and genetic markers.Semantic proximity Read ↗

A novel approach for haplotype-based association analysis using family data.Semantic proximity Read ↗

Haplotype association analysis of human disease traits using genotype data of unrelated individuals.Semantic proximity Read ↗

Identification of risk-related haplotypes with the use of multiple SNPs from nuclear families.Semantic proximity Read ↗

Estimating haplotype relative risks in complex disease from unphased SNPs data in families using a likelihood adjusted for ascertainment.Semantic proximity Read ↗

Power and related statistical properties of conditional likelihood score tests for association studies in nuclear families with parental genotypes.Semantic proximity Read ↗

Inference on haplotype/disease association using parent-affected-child data: the projection conditional on parental haplotypes method.Semantic proximity Read ↗

Parental genotype reconstruction: applications of haplotype relative risk to incomplete parental data.Semantic proximity Read ↗

A Bayesian approach to disease gene location using allelic association.Semantic proximity Read ↗

Sample size calculations for classical association and TDT-type methods using family data.Semantic proximity Read ↗

On the advantage of haplotype analysis in the presence of multiple disease susceptibility alleles.Semantic proximity Read ↗

Comparison of family based haplotype methods using intragenic SNPs in candidate genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.